EktaH Shows ~50% Reduction in Post-GLP-1 Weight Rebound with Novel Obesity Treatment and Reports Positive Phase I Data
— First-in-class oral mechanism triggers natural satiety hormones, addressing key limitations of GLP-1 therapies
— Phase I data demonstrate fat mass reduction, preservation of lean mass, 80% responder rate, and no serious adverse events
EktaH, a clinical-stage biotechnology company, today reported positive preliminary Phase I results and preclinical data for its lead compound NKS-3, a modified fatty acid molecule and the first oral therapy designed to address key limitations of current GLP-1 obesity treatments.
While GLP-1 receptor agonists such as semaglutide and tirzepatide have demonstrated significant weight loss, patients typically regain their baseline weight within 18 months of discontinuing treatment. In addition, current therapies are associated with loss of lean muscle mass and gastrointestinal side effects that drive discontinuation rates above 60%. Equally important, up to one third of obese individuals do not respond to GLP-1 treatments.
C-mo Medical Solutions Receives CE Mark for Its Novel AI-Powered Cough Monitoring Solution
- Regulatory milestone supports broader adoption of C-mo’s privacy-preserving technology in clinical research and medical practice
- Approval covers the biosensor, automated cough monitoring algorithms and software platform
- C-mo allows precise, objective monitoring of cough frequency and intensity across multiple indications
C-mo Medical Solutions, a leading provider of next-generation cough monitoring technology, today announced that it has received CE Mark for C-mo System, its AI-powered cough monitoring solution.
C-mo System is a non-invasive, Class IIa medical device, now CE-marked under EU MDR 2017/745, for monitoring cough in patients across a broad range of indications. The certification covers the biosensor, the automated cough monitoring algorithms and the software platform. Read more…
Nature Translational Psychiatry Study Reveals Distinct Functional Neuronal Signatures in Patient-Derived Brain Organoids with Itay&Beyond’s Neurotech Platform
— Peer-reviewed publication validates the potential of Itay&Beyond’s human CNS platform for advanced disease stratification, translational research, and future therapeutic discovery
— Proprietary platform enables functional analysis of how human neurons behave and communicate in biologically relevant disease models across a broad range of neurodevelopmental and neurodegenerative indications
Itay&Beyond, a neurotech CNS company with a patient-derived brain organoid platform for next-generation neuropsychiatric and neurological drug discovery and development, today announced the publication of novel data in Nature Translational Psychiatry1demonstrating that its pioneering brain-on-a-chip platform, derived from patient urine samples, can reveal functionally distinct neuronal signatures across subpopulations of autism spectrum disorder (ASD). Read more…
